Human Synoviocytes -1 vial

Species : Human Description: Human synoviocytes (HS), the predominant cell type of healthy synovial tissue, are fibroblast-like cells The Synoviocytes form a distinct structure called the synovial lining layer Electron microscopy revealed extensive cell-to-cell contacts within the lining layer The Synoviocytes produce synovial fluid components and are responsible for absorption from the joint cavity, and for blood/synovial fluid exchanges The synoviocytes proliferate, show anchorage-independent growth, and also secrete a variety of effector molecules that promote inflammation and joint destruction and, themselves are part of a complex network of autocrine and paracrine acting factors The synoviocytes express cadherin-11 providing new insight into synovial tissue organization and morphogenesis and of interest as a therapeutic targetHS from AcceGen Research Laboratories are isolated from human synovium HS are cryopreserved at passage one cultures and delivered frozen Each vial contains >5×10^5 cells in 1 ml volume HS are characterized by their fibroblast-like morphology, growth pattern and immunocytochemistry of CD 90 and fibronectin HS are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi HS are guaranteed for 15 population doublings at the conditions provided by AcceGen Research Laboratoriesand directly supplied to your lab by Gentaur's warehouse.